Table 2.
[11C]FLB 457 PET scan parameters
| Condition | Injected dose (mCi) | Specific activity (Ci mmol−1) | Injected mass (ug) | Free Fraction in plasma (%) | VND (mL cm−3) | ||
|---|---|---|---|---|---|---|---|
| Healthy Controls | Baseline | Mean | 7.1 | 8891 | 0.39 | 34.7 | 4.27 |
| SD | 1.7 | 5689 | 0.17 | 5.9 | 1.23 | ||
| Amphetamine | Mean | 7.7 | 8741 | 0.39 | 34.3 | 4.04 | |
| SD | 1.4 | 4307 | 0.13 | 5.1 | 0.86 | ||
| Alcohol Dependence | Baseline | Mean | 7.6 | 11369 | 0.36 | 38.9 | 4.43 |
| SD | 1.4 | 8871 | 0.17 | 7.6 | 1.01 | ||
| Amphetamine | Mean | 6.8 | 6995 | 0.46 | 39.3 | 4.37 | |
| SD | 1.9 | 4736 | 0.16 | 7.3 | 0.97 |
Values are mean and standard deviation (SD), n = 21 per group
* p ≤ 0.05, paired t-tests (baseline vs. amphetamine)