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. Author manuscript; available in PMC: 2014 Aug 3.
Published in final edited form as: FEBS Lett. 2013 Mar 21;587(9):1392–1398. doi: 10.1016/j.febslet.2013.03.016

Fig. 2.

Fig. 2

Increase of Rgs2 transcripts and RGS2 protein following treatment with norepinephrine or a cAMP analog. (A) Rgs2 transcription was induced by 1 µM norepinephrine application, and reached its peak 2 h after stimulation. Significant induction of Rgs2 was found 1 to 4 h after stimulation (P < 0.05, one-way ANOVA vs expression level at 0 h, n = 3 each). (B) RGS2 protein increased within 2 h by treatment with 1 µM norepinephrine (P < 0.05, one-way ANOVA vs expression level at 0 h, n = 3 each). Inset shows a representative Western blot result of RGS2 protein expression following norepinephrine stimulation. (C) Application of the cAMP analog, dibutyryl–cAMP, induced transcription of Rgs2 (Control vs DBcAMP, 4.3 ± 0.55% vs 100.0 ± 9.41%; P < 0.05, two-tailed t-test, n = 3 each). For further details see Section 2.