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. Author manuscript; available in PMC: 2014 Oct 7.
Published in final edited form as: Nat Commun. 2014 Apr 7;5:3470. doi: 10.1038/ncomms4470

Table 3.

Gold-catalyzed alkyne hydration.

graphic file with name nihms568869t3.jpg
Catalyst Yield/TON
R = n-decyl, [Au] (500 ppm),
toluene (0.25 × n mL), 5 h		 R = n-butyl, [Au] (100 ppm),
MeOH (0.3 × n mL), 6 h
JohnPhosAuNTf2 8%/160 44%/4400
IPrAuNTf2 9%/180 69%/6900
L8AuNTf2 38%/760 100%/10000