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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: J Immunol. 2014 Jun 9;193(2):757–763. doi: 10.4049/jimmunol.1400188

Figure 3. Rapamycin impairs effective control of WNV, resulting in increased mortality.

Figure 3

Mice were infected with 103 pfu WNV s.c. (A) On day 10 post-infection brains were harvested and viral titer was determined by plaque assay. n=6-12 mice/group, representative of 2 independent experiments. Unpaired Mann-Whitney nonparametric test was used to determine statistical significance. (B) Mice were tracked for survival for 30 days after infection, with n=20-22 mice/group, representative of 2 independent experiments. Statistical significance was determined by Log-rank test. (A and B) Control groups are represented by open circles, rapa groups are represented with filled squares.