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. Author manuscript; available in PMC: 2014 Aug 3.
Published in final edited form as: Science. 2013 Jun 7;340(6137):1211–1214. doi: 10.1126/science.1234393

Fig. 2. Dynamic evolution of Umbrea following birth.

Fig. 2

(A) PCR to shared syntenic sites followed by sequencing (Fig. S6) revealed the presence and structure of Umbrea genes. Asterisks indicate strong support for key branch points in the phylogeny(25), suggesting that Umbrea was lost at least three times. Umbrea is presented with HP1 canonical domains: chromodomain (CD, green) and chromoshadow domain (CSD, blue). (B) Localization of GFP-tagged HP1B lacking its CD is diffuse in D. melanogaster Kc cell nuclei (GFP is green, anti-Cid is magenta, and DAPI staining of DNA in blue, bar = 5 microns). (C) In contrast, HP1B-CD-hinge fused to Umbreamel delocalizes it from centromeres.