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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Semin Arthritis Rheum. 2014 Feb 11;44(1):47–54. doi: 10.1016/j.semarthrit.2014.02.002

Table 1.

Cross-sectional studies of spine bone mineral density in children on glucocorticoid therapy

References Condition, sample size Glucocorticoid
dose and duration
Quality
score
Falcini et al. [16] JIA cases, n = 16 Deflazacort median 0.8 mg/kg/day 15/21
JIA controls, n = 24 0.3–2.0 mg/kg/day
Healthy controls, n = 40 Range: 6 months to 3 years
Celiker et al. [20] JIA cases, n = 17 Prednisolone 14/20
JIA controls, n = 11 ≥ 7.5 mg/day
Healthy controls, n = 45 ≥ 5 months
Brik et al. [19] JIA cases, n = 10 Prednisone 16/21
JIA controls, n = 7 0.4 mg ± 0.2 mg/kg/day
Healthy controls, n = 18 2.5 ± 1.3 years
Kashef et al. [21] JIA or SLE cases, n = 20 GC not specified 17/21
Healthy controls, n = 20 6.6 ± 3.2 mg/day
≥ 6 months

JIA = juvenile inflammatory arthritis; SLE = systemic lupus erythematosus; GC = glucocorticoid therapy.