Table 2.
| A: Association of high frequency of HLA-B*44 allele with low/moderate prevalence of HSV-2 infection in various regions of the world. | |||
|---|---|---|---|
| Sub regions | Prevalence of HSV-2 infection | HLA-B*44 allele frequency 1 | |
| Asia | Bangladesh | Low | High |
| Japan | Low | High | |
| Europe | Basque | Low | Most frequent HLA-B (Caucasoid) |
| France | Low | Most frequent HLA-B | |
| North Ireland | Low | 35.7% | |
| Spain | Low (3.9% men genital herpes) | Most frequent HLA-B | |
| United Kingdom | Low (4% England) | 32% | |
| Middle East | Israel | Low | High |
| North Africa | Algeria | Low | High |
| Morocco | Low | High | |
| Tunisia | Low | High | |
| Sub-Saharan Africa | Cameroon | 55% women, 36% men | Low |
| Kenya | 55% women, 36% men | Low | |
| South Africa | High | Low | |
| B: Association of high frequency of HLA-A*24, HLA-B*27, HLA-B*53, and HLA-B*58 alleles with moderate/high prevalence of HSV-2 infection in various regions of the world. | ||||||
|---|---|---|---|---|---|---|
| Sub regions | HSV-2 infection prevalence | HLA-A*24 allele frequency 1 | HLA-B*27 allele frequency 1 | HLA-B*53 allele frequency 1 | HLA-B*58 allele frequency 1 | |
| Asia | Oriental Asia | Low | - | - | <3% | - |
| Bangladesh | Low (7% women genital herpes) | - | - | - | Low | |
| Japan | Low | - | 0.1-0.5% | - | Low | |
| Russia | 21-30% | - | 10.2% | - | - | |
| Taiwan | High | 48.9% | 15% | - | - | |
| Brunei Darussalam | 61.8% women and 47.8% men aged 15-49 | Most frequent HLA-A | - | - | - | |
| China | 2.9% | - | - | |||
| Mongolia | <2% | - | - | |||
| North Korea | <2% | - | - | |||
| Singapore | - | - | - | |||
| South Korea | <2% | - | - | |||
| Europe | Caucasoid Europe | Low | - | - | <3% | - |
| Belgium | Low | - | 14.3% | - | - | |
| Denmark | Low | - | 24% | - | - | |
| France | Low | - | 12% | - | - | |
| Germany | Low | - | 13% | - | - | |
| Norway | Low | - | 24% | - | - | |
| Romania | Low | - | 11.2% | - | - | |
| Spain (men) | 3.9% genital herpes | - | - | - | Low | |
| Sweden | Low | - | 16% | - | - | |
| United Kingdom | Low | Low | ≤ 8% (*27:05) | - | - | |
| Middle East | Arab Nations | Low | - | low | - | Low |
| Israel | Low | - | low | - | Low | |
| North Africa | Morocco | Low | - | 4% | <3% (Caucasoid) | - |
| Algeria | Low | - | 4% | <3% (Caucasoid) | - | |
| Tunisia | Low | - | 4% | <3% (Caucasoid) | - | |
| Lybia | Low | - | 4% | <3% (Caucasoid) | - | |
| Egypt | Low | - | 4% | <3% (Caucasoid) | - | |
| North America | United States (African Americans) | High | - | ≤ 3% | 25.5%, most frequent HLA-B | - |
| United States (Caucasoid) | Low | - | - | <3% | - | |
| South/Central America | South/Central America | Moderate | - | < 2% | - | - |
| Costa Rica | 39% genital herpes women | 2nd most frequent HLA-A | - | - | - | |
| Columbia (Black, Mestizo) | 50% women | Most frequent HLA-A | - | - | - | |
| Republic of Cuba | High | - | - | Most frequent HLA | - | |
| Sub-Saharan Africa | sub-Saharan Africa (Blacks) | High | - | ≤ 3% | - | 2nd most frequent HLA |
| Botswana | High | - | - | - | 17.9% | |
| South Africa | High | - | - | - | Most frequent HLA-B, 39% | |
| Burkina Faso | High | - | Most frequent HLA | - | - | |
| Cameroun | 55% women, 36% men | 3rd most frequent HLA-A | - | - | Most frequent HLA-B | |
| Kenya | - | - | - | |||