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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Immunotoxicol. 2014 Feb 3;12(1):64–73. doi: 10.3109/1547691X.2014.882449

Figure 2. Lung inflammation in SRA KO following 1 wk recovery after repetitive ODE exposures.

Figure 2

Mice intra-nasally treated with saline or ODE daily for 3 wk and subsequently rested (no intra-nasal treatments) for a 1 wk recovery phase. A representative 4–5-µm thick section (H&E stained) of one mouse per treatment group is shown (10× magnification). (A) Saline. (B) Wild-type (WT) SRA+/+ treatment group. (C) KO SRA−/− treatment group. (D) Mean semi-quantitative distribution of inflammatory scores of lung lymphoid aggregates, bronchiolar inflammation and alveolar inflammation in mice (n = 4–5 mice/group). Error bars represent SE. Statistically significant (*p < 0.05, **p < 0.01, ***p < 0.001) vs. saline. #p < 0.05 and ###p < 0.001: significant differences between groups as indicated (1-way ANOVA with Tukey’s post-hoc comparison). Line scale represents 100 µm.