Fungal recovery from sinus lavage is more likely in the context of Th2-associated airway disease. (A-C) Percent of patients yielding positive fungal cultures from sinus lavage comparing (A) control patients to CRS without nasal polyps, CRS with nasal polyps, and AFRS patients; B) control patients and non-asthmatics to asthmatics; and C) Non-Th2-associated to Th2-associated patients. * p<0.05, ** p<0.01, *** p<0.001. (D, E) Representative Sabouraud’s plate fungal cultures of sinus lavage fluid from two subjects. (F) Photomicrograph of unstained sinus lavage mucus from a representative AFRS patient showing extensive hyphal network (400×). §Control is a subset of all non-asthmatics.