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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Inherit Metab Dis. 2014 Feb 3;37(5):735–743. doi: 10.1007/s10545-013-9675-2

Figure 5. Effect of NTBC treatment upon brain dopamine and its metabolites in Pahenu2/enu2 mice.

Figure 5

NTBC treatment was associated with significant increases in the brain content of dopamine and its degradation products. The deficit in dopamine turnover ((DOPAC + HVA)/DA) exhibited by Pah−/− mice was corrected by NTBC treatment. Data are presented as mean ± SEM. Statistical analysis utilized one-way ANOVA with intergroup p values calculated using Bonferonni’s Multiple Comparison Test.