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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Trends Cardiovasc Med. 2014 Apr 1;24(5):202–205. doi: 10.1016/j.tcm.2014.03.003

Figure A.

Figure A

schematic representation of the signaling pathways controlling growth and death of cardiomyocytes that are regulated by Nox isoforms. Nox2 and Nox4 are localized in different subcellular compartments and regulate signaling mechanisms locally or globally to affect metabolism, hypertrophy, autophagy and apoptosis.