Table 1.
Sample characteristics and clinical results
| Variable | Healthy Controls (n=31) | IBSa patients (n=12) | P value |
|---|---|---|---|
| Gender (n) | |||
| Male | 15 | 3 | - |
| Female | 16 | 9 | - |
| Race (n) | |||
| Asian | 7 | 2 | - |
| African American/Black | 13 | 8 | - |
| Caucasian | 7 | 1 | - |
| Other | 4 | 1 | - |
| Age | 27.9±8.5 | 29.2±7 | p>0.05 |
| Range (years) | 13–45 | 16–45 | |
| IBS-Diarrhea | - | 5 | |
| IBS-Constipation | - | 5 | |
| IBS-Mixed | - | 2 | |
| BMIb | 24.5±4.7 | 26.6±5.8 | p>0.05 |
| Range | 28.5–48.2 | 20.5–41.3 | |
| Hematocrit | 40.4±5.0 | 39.4±4.6 | p>0.05 |
| Range (%) | 28.5–48.2 | 30.2–47.9 | |
| CRPc | 1.8±1.8 | 3.1±4.8 | p>0.05 |
| Range (mg L−1) | 0.2–7.3 | 0.2–17.5 | |
| ESRd | 9.6±8.4 | 12.5±7.7 | p>0.05 |
| Range (mm/hr) | 2.0–30.0 | 3.0–25.0 | |
| Alk. Phos.e | 75.2±56.6 | 66.0±19.6 | p>0.05 |
| Range (U L−1) | 36.0–367.0 | 40.0–110.0 | |
| ALTf | 27.5±10.6 | 28.6±13.7 | p>0.05 |
| Range (U L−1) | 15.0–66.0 | 17.0–55.0 | |
| ASTg | 17.8±8.9 | 20.5±15.0 | p>0.05 |
| Range (U L−1) | 6.0–53.0 | 6.0–61.0 | |
| GGTPh | 25.0±12.6 | 34.2±28.3 | p>0.05 |
| Range (U L−1) | 9.0–57.0 | 11.0–113.0 | |
| Amylase | 64.5±20.8 | 71.4±20.9 | p>0.05 |
| Range (U L−1) | 29.0–117.0 | 46.0–109.0 | |
| Lipase | 127.6±46.5 | 168.5±72.3 | p=0.034 |
| Range (U L−1) | 63.0–255.0 | 85.0–357.0 |
All values expressed as mean ±standard deviation.
a
IBS, Irritable Bowel Syndrome.
b
BMI, Body Mass Index.
c
CRP, C-reactive protein.
d
ESR, Erythrocyte sedimentation rate.
e
Alk. Phos., Alkaline phosphatase.
f
ALT, Alanine transaminase.
g
AST, Aspartate Aminotransferase.
h
GGTP, Gamma Glutamyl Transpeptidase. Normal ranges – Hematocrit: 34.1–44.9%, CRP: <3.0mg L−1, ESR: <42mm hr−1, Alk Phos.: 37–116 U L−1, ALT: 6–41 U L−1, AST: 9–34 U L−1, GGTP: 5–85 U L−1, Amylase: 25–115 U L−1, Lipase: 76–491 U L−1.