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. Author manuscript; available in PMC: 2015 Feb 15.
Published in final edited form as: Lancet. 2013 Nov 20;383(9917):614–621. doi: 10.1016/S0140-6736(13)62302-8

Figure 2. Kaplan-Meier estimated event rate by (A) as-randomised and (B) as-treated.

Figure 2

Crosses depict censored patients. HR=hazard ratio. (A) Log-rank χ2=16·07; p<0·0001. (B) Log-rank χ2=26·9, p<0·0001. Seven patients in the medical management crossed over to interventional therapy. 20 patients in the interventional therapy group did not receive interventional therapy and are deemed crossovers to medical management. Three additional patients randomised to interventional therapy had a stroke before the initiation of interventional therapy and were placed in the medical management group for the as-treated analysis.