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. 2014 Jul 9;2014:417986. doi: 10.1155/2014/417986

Figure 6.

Figure 6

FITC-dextran flux assay. Permeability is defined by P o (cm/s). There was a significant increase in permeability of cells cultured under high glucose (HG) conditions or transfected with caspase-14 plasmid at different time points (1, 3, and 6 h) compared with cells grown under normal glucose (NG) conditions or HG-treated cells transfected with caspase-14 siRNA (*P < 0.0001). Caspase-14 siRNA is significantly lower than high glucose at 3 h and 6 h ($ P < 0.001). Please note that caspase-14 plasmid has the same permeability effect as HG at 3 and 6 h (n = 4, *P < 0.05 versus control and HG + caspase-14 siRNA, # P < 0.05 versus control plasmid).