Table 2.
Antihyperglycemic activity of SCEE in glucose loaded alloxan induced diabetic animals.
| Treatment | Dose (mg/kg) | Blood glucose concentration (mg/dL) | |||
|---|---|---|---|---|---|
| 0 min | 60 min | 120 min | 180 min | ||
| SCEE | 150 | 252.0 ± 4.4 | 315.0 ± 5.0∗ | 321.7 ± 12.8∗ | 266.0 ± 5.2∗ |
| 300 | 247.5 ± 5.0 | 292.0 ± 7.0∗ | 303.3 ± 5.7∗ | 236.7 ± 12.5∗ | |
| Nondiabetic | — | 84.5 ± 4.5 | 140.0 ± 6.4 | 112.0 ± 3.6 | 92.0 ± 4.8 |
| Diabetic control | — | 240.0 ± 4.5 | 379.7 ± 9.5 | 410.0 ± 5.0 | 342.0 ± 19.6 |
| Glibenclamide | 5 | 233.0 ± 5.7 | 270.0 ± 6.2∗ | 295.0 ± 5.0∗ | 228.7 ± 3.2∗ |
Values expressed as means ± SD. ∗Significance difference (P < 0.05) against diabetic control. SCEE: S. cordata ethyl acetate fraction.