Table 3.
Hypoglycemic activity of SCEE in normal fasting animals.
| Treatment | Dose (mg/kg) | Blood glucose concentration (mg/dL) | |||
|---|---|---|---|---|---|
| 0 min | 60 min | 120 min | 180 min | ||
| SCEE | 150 | 84.0 ± 1.5 | 67.5 ± 1.5∗ | 61 ± 1.5∗ | 59 ± 1.5∗ |
| 300 | 82.2 ± 2.5 | 61.6 ± 1.5∗ | 51 ± 1.5∗ | 55 ± 1.7∗ | |
| Nondiabetic | — | 81.6 ± 2.1 | 79.4 ± 1.3 | 77 ± 1.2 | 75 ± 1.0 |
| Glibenclamide | 5 | 84.5 ± 1.5 | 52.5 ± 2.5∗ | 47 ± 2.5∗ | 49 ± 1.7∗ |
Values expressed as means ± SD. ∗Significance difference (P < 0.05) is expressed against nondiabetic. SCEE: S. cordata ethyl acetate fraction.