Table 8.
Group | Protein | TBARS | H2O2 | Nitrite content |
---|---|---|---|---|
(μg/mg tissue) | (nM/min/mg protein) | (nM/min/mg tissue) | (μM/mL) | |
Pancreas | ||||
Normal control | 5.0 ± 0.5a | 1.9 ± 0.2d | 5.5 ± 0.5d | 64.6 ± 2.0e |
Diabetic + glibenclamide | 4.1 ± 0.3bc | 2.3 ± 0.2cd | 6.9 ± 0.4cd | 70.3 ± 0.6de |
Diabetic control | 1.9 ± 0.2e | 4.9 ± 0.4a | 12.5 ± 0.5a | 102.3 ± 2.5a |
Diabetic + SCEE 150 mg/kg | 2.6 ± 0.3de | 3.5 ± 0.2b | 9.7 ± 0.7b | 91.3 ± 3.0b |
Diabetic + SCEE 300 mg/kg | 4.2 ± 0.3b | 2.6 ± 0.2c | 6.8 ± 0.3cd | 74.0 ± 1.7cd |
| ||||
Liver | ||||
Normal control | 6.6 ± 0.5a | 2.4 ± 0.1e | 6.5 ± 0.4e | 56.8 ± 1.9d |
Diabetic + glibenclamide | 5.2 ± 0.4b | 2.9 ± 0.1d | 8.3 ± 0.7cd | 62.0 ± 1.8cd |
Diabetic control | 2.2 ± 0.3d | 6.9 ± 0.3a | 12.9 ± 0.9a | 97.0 ± 3.6a |
Diabetic + SCEE 150 mg/kg | 3.5 ± 0.4c | 4.7 ± 0.3c | 9.4 ± 0.5bc | 77.6 ± 2.5b |
Diabetic + SCEE 300 mg/kg | 5.7 ± 0.3ab | 2.8 ± 0.1de | 7.5 ± 0.5de | 63.6 ± 0.6cd |
| ||||
Testis | ||||
Normal control | 4.7 ± 0.3a | 1.5 ± 0.2c | 5.3 ± 0.3d | 57.5 ± 2.7d |
Diabetic + glibenclamide | 3.9 ± 0.2b | 2.0 ± 0.1c | 6.3 ± 0.6cd | 64.6 ± 1.5cd |
Diabetic control | 1.7 ± 0.2d | 5.6 ± 0.3a | 11.4 ± 0.6a | 93.3 ± 4.1a |
Diabetic + SCEE 150 mg/kg | 2.6 ± 0.4c | 3.8 ± 0.2b | 8.4 ± 0.5b | 82.2 ± 4.0b |
Diabetic + SCEE 300 mg/kg | 4.2 ± 0.2ab | 2.1 ± 0.6c | 6.3 ± 0.3cd | 66.0 ± 1.7c |
Values expressed as means ± SD. Means ± SD with different superscript letters (a–d) within the column indicate significant difference (P < 0.05). SCEE: S. cordata ethyl acetate fraction.