Table 1.
Series previously reported.
| Author, year (reference number) | Patient Sex/Age | Clinical presentation |
|---|---|---|
| Garlan and Armitage, 1933 [4] | 2 patients | Age and gender not mentioned in the paper |
| Coleman and Meredith, 1940 [5] | 1 patient | Primary optic atrophy and bitemporal hemianopia |
| Glass and Davis, 1944 [46] | M/54 Y | Panhypopituitarism with febrile episodes |
| Brooks et al., 1973 [6] | F/33 Y | Headache, diminution of vision, and past history of pulmonary Koch |
| Eckland et al., 1987 [7] | F/37 Y | Bitemporal headache, vomiting, and diplopia. Right sixth nerve palsy, right temporal hemianopia and a depressed right corneal reflex lateral gaze to the right |
| Esposito et al., 1987 [8] | F/54 Y | Headache with loss visual acuity in the left eye and diplopia on left lateral gaze. History pulmonary tuberculosis at the age of 22 |
| Delsedime et al., 1988 [9] | F/45 Y | Isolated tuberculous granuloma of the hypophysis with no other systemic localizations |
| Kamiya et al., 1991 [10] | M/41 | Headache, history of pulmonary tuberculosis at the age of 20 |
| Taparia et al., 1992 [34] | M/40 Y | Intermittent dull headache. Visual acuity reduced and bilateral optic atrophy |
| Ghosh and Chandy, 1992 [11] | F/35 Y | Headache, vomiting, blurred vision, amenorrhea, and galactorrhea |
| Ranjan and Chandy, 1994 [36] | Five patients | In four cases the clinical and radiological diagnosis was that of a pituitary adenoma. One patient presented similar to a subarachnoid haemorrhage, but the CSF analysis was suggestive of tuberculous meningitis. All these patients presented either with intermittent headache. Hypopituitarism was diagnosed in two patients and one patient had an associated galactorrhoea-amenorrhoea syndrome. Only one patient had a bitemporal field cut. In all other patients ophthalmological examination was normal |
| Pereira et al., 1995 [12] | F/55 Y | Left sixth nerve palsy and headaches |
| Ashkan et al., 1997 [13] | F/33 Y F/31 Y |
Secondary amenorrhea, fatigue, headache and weight loss Secondary amenorrhea, galactorrhea and headache |
| Petrossians et al., 1998 [35] | F/54 Y | Extreme weakness, headache, and vomiting |
| Gazioğlu et al., 1999 [14] | F/34 Y | Acromegaly, oligomenorrhea, and hypertrichosis |
| Sharma et al., 2000 [15] | 18 cases Range: 8–43 Y |
The duration of symptoms varied from 15 days to 2 years (average 4 months); the most common symptoms being headache followed by decrease or loss of vision. Five patients had features of panhypopituitarism whereas three had raised prolactin (PRL) levels. In three patients, there was past history of pulmonary tuberculosis |
| Basaria et al., 2000 [16] | F | Pituitary mass, presumed preoperatively to be an adenoma. The patient did not have history of tuberculosis infection |
| Arunkumar and Rajshekhar, 2001 [3] | M/27 Y | 3 previous episodes of pituitary apoplexy |
| Kumar et al., 2001 [17] | 1 patient | Pituitary mass with clinical and MRI findings consistent with adenoma |
| Manghani et al., 2001 [37] | F/24 Y | Headache and loss of libido |
| Domingues et al., 2002 [18] | F/46 Y | Confusion and hypopituitarism with no evidence of systemic tuberculosis |
| Stalldecker et al., 2002 [19] | F/16 Y | Headache, hyperpyrexia, polyuria, polydipsia and amenorrhea |
| Desai et al., 2003 [20] | F/15 Y F/19 Y F/22 Y F/30 Y M/47 Y |
Headache, amenorrhoea, galactorrhoea, diminution of vision, bitemporal hemianopia, past history of pulmonary Koch Headache, amenorrhoea Headache, amenorrhoea, diminution of vision, bitemporal hemianopia, past history of Koch's cervical adenopathy Headache, oligomenorrhoea, galactorrhoea Headache |
| Satyarthee and Mahapatra, 2003 [21] | F/32 Y | Diabetes insipidus and secondary amenorrhea |
| Harzallah et al., 2004 [22] | F/52 Y M/62 Y |
Extreme weakness, headache, vomiting, meningeal syndrome and third cranial nerve palsy Generalized tonic-clonic seizure, low grade fever and mental confusion |
| Trabelsi et al., 2005 [23] | F/42 Y | History of erythema nodosum, poliuria, polydipsia, amenorrhea and galactorrhea |
| Deogaonkar et al., 2006 [24] | F/27 | Headaches, left ptosis and left facial numbness. Drowsy and obtunded, tachycardia with blood pressure normal. Left facial hypoesthesia in left V1 and V2 distribution. Her hormone profile did not reveal any abnormality |
| Bayindir et al., 2006 [25] | 1 patient | Age and gender no mentioned in the article |
| Sunil et al., 2007 [2] | M/42 Y | Polyuria, polydypsia, polyphagia, and decreased libido secondary to diabetes mellitus |
| Yilmazlar et al., 2007 [26] | F/37 Y | Galactorrhea and menstrual irregularity |
| Husain et al., 2008 [27] | F/40 Y | Headache and fatigue |
| Rao et al., 2008 [28] | F/47 Y | Diabetic, hypothyroid and hypertensive. Presented with headache, vomiting, transient blurring of vision and galactorrhea. |
| Behari et al., 2009 [29] | 8 cases, Range: 15–40 Y M : F ratio = 5 : 3 | Range of duration of clinical symptomatology, 6 months–3 years Headache was again the predominant symptom in most patients, which resulted from raised intracranial pressure due to both the large size of the lesion as well as the coexisting hydrocephalus. One patient presented with headache due to pachymeningitis, one due to stretching of the diaphragma sellae by an intrasellar tuberculous abscess, and the third due to clival infiltration. Three of our patients had either a previous history of tuberculosis or a concomitant lesion at some other site |
| Mittal et al., 2010 [30] | F/40 Y | Persistent headache and blurred vision on the left side |
| Domiciano et al., 2010 [31] | F/33 Y | Nodular RA who was being treated with methotrexate, sulfasalazine and corticosteroids and presented with subcutaneous nodules simultaneously with aseptic meningitis. Mycobacterium tuberculosis was identified in cultures from a biopsy of an axillary nodule. The patient also developed polyuria and polydipsia with normal glycemia |
| Shukla et al., 2010 [32] | M/68 Y | Holocranial headache of four months duration with left temporal hemianopia, with visual acuity of 6/6, without any localizing sign |
| Furtado et al., 2011 [33] | F/31 Y | Panhypopituitarism |