Table 5.
Summary of a retrospective review of ultrasound exams in 149 mice showing the occurrence of common underlying etiologies involved in urinary tract obstructions in mice and the presence of renal pelvic dilation
| Signalment | Necropsy and ultrasound findings | Renal pelvic dilation | |
|---|---|---|---|
| Mouse urologic syndrome | C57BL/6J M, 24 mo. | Enlarged SVs (bilateral), echogenic bladder coagulum. | Yes |
| C57BL/6J M, 24 mo. | Enlarged SVs (bilateral) with adenitis and culture + for E. cloacae and Pseudomonas aeruginosa echogenic coagulum in bladder | No | |
| C56BL/6J M, 25 mo. | Enlarged SVs (bilateral), bladder distension with luminal echogenic material, urethral dilation | Yes, bilateral | |
| FVB/N M, 22 mo. | Enlarged SVs (bilateral), bladder distension with thick echogenic material in lumen | No | |
| FVB/N M, 24 mo. | Enlarged SVs (bilateral), luminal hemorrhage bladder, cystic preputial and bulbourethral glands, and paraphymosis | No | |
| C57BL/6J M, 29 mo. | Enlarged SVs, bladder distension with echogenic debris, urethral dilation with echogenic debris (in addition had histiocytic sarcoma of the spleen) | Yes, bilateral | |
| B6;129 M, 29 mo. | Enlarged SVs, bladder distension with echogenic coagulum. | Yes, right side | |
| Cystolithiasis | Signalment | Necropsy and ultrasound findings | Renal pelvic dilation |
| BALB/cJ F, 21 mo. | Bladder calculi | No | |
| Slc26a6−/− KO M, 20 mo. | Calcium oxalate calculi in bladder and renal cortical mineralization | No | |
| Slc26a6−/− M, 24 mo. | Calcium oxalate calculi in bladder | No | |
| Slc26a6−/− M, 26 mo. | Calcium oxalate calculi in bladder | No | |
| Myoglobin+/+ M, 24 mo. | Bladder calculi with Proteus mirabilis in lumen | No | |
| Slc26a6−/− KO 3 | Bladder calculi (calcium oxalate) | No | |
| Myoglobin+/+ M, 24 mo. | Bladder calculi, urine culture + for Proteus mirabilis | Yes | |
| Slc26a6−/− M, 35 mo. | Bladder calculi, calcium oxalate | No | |
| Spontaneous | Signalment | Concurrent pathological findings | Renal pelvic dilation |
| hydronephrosis | CAST/EiJ F, 26 mo. | Splenic follicular hyperplasia | Yes, right side |
| Other | Signalment | Related pathological conditions | Renal pelvic dilation |
| C57BL6/J M, 12 mo. | Inguinal testicular herniation, preputial keratin plug | Yes, bilateral |
mo.=month, SVs = seminal vesicle.