Table 2. Likelihood of receipt of lung cancer surgery, by SEP, adjusted for selected patient, tumour and system factors, for full cohort.
| |
Receipt of surgery (2894/28 733) |
Unadjusted (n=28 733) |
Adjusted – sex, age, year, CCI, GP referral, stage, PS, histological subtype (n=28 733,
R2=35.29%) |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | N | % | OR | (95% CI) | P | OR | (95% CI) | P | ||
| Deprivation quintile |
2894 |
10.1 |
|
|
|
<0.001 |
|
|
|
0.01 |
| 1 (Least deprived) | 400 | 11.8 | 1.00 | |||||||
| 2 | 458 | 11.0 | 0.92 | 0.80 | 1.06 | 0.91 | 0.77 | 1.08 | ||
| 3 | 512 | 10.6 | 0.88 | 0.77 | 1.01 | 0.97 | 0.82 | 1.15 | ||
| 4 | 613 | 9.1 | 0.75 | 0.66 | 0.86 | 0.80 | 0.68 | 0.94 | ||
| 5 (Most deprived) |
911 |
9.5 |
0.78 |
0.69 |
0.89 |
|
0.82 |
0.71 |
0.96 |
|
| Sex |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| Female | 1405 | 10.6 | 1.00 | |||||||
| Male |
1489 |
9.6 |
|
|
|
|
0.78 |
0.71 |
0.85 |
|
| Age group |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| <60 | 560 | 15.2 | 1.00 | |||||||
| 60–69 | 1118 | 14.7 | 1.04 | 0.92 | 1.19 | |||||
| 70–79 | 1048 | 10.2 | 0.79 | 0.69 | 0.90 | |||||
| 80+ |
168 |
2.3 |
|
|
|
|
0.22 |
0.18 |
0.26 |
|
| Year of diagnosis |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| 2006 | 505 | 9.1 | 1.00 | |||||||
| 2007 | 547 | 9.6 | 1.10 | 0.95 | 1.27 | |||||
| 2008 | 502 | 8.6 | 0.96 | 0.83 | 1.12 | |||||
| 2009 | 682 | 11.6 | 1.50 | 1.31 | 1.88 | |||||
| 2010 |
658 |
11.4 |
|
|
|
|
1.58 |
1.29 |
1.92 |
|
| CCI score |
2894 |
10.1 |
|
|
|
|
|
|
|
0.0002 |
| 0 | 482 | 12.0 | 1.00 | |||||||
| 1–2 | 326 | 9.2 | 0.90 | 0.75 | 1.07 | |||||
| 3+ | 83 | 9.0 | 1.01 | 0.75 | 1.36 | |||||
| Missing | 1021 | 10.0 | 0.91 | 0.79 | 1.06 | |||||
| Unavailable |
982 |
9.7 |
|
|
|
|
0.69 |
0.58 |
0.81 |
|
| GP referral |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| No | 979 | 7.4 | 1.00 | |||||||
| Yes |
1915 |
12.4 |
|
|
|
|
1.27 |
1.15 |
1.40 |
|
| Stage |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| I | 607 | 51.2 | 1.00 | |||||||
| II | 195 | 35.3 | 0.43 | 0.33 | 0.56 | |||||
| III | 144 | 6.3 | 0.04 | 0.04 | 0.06 | |||||
| IV | 55 | 1.5 | 0.01 | 0.01 | 0.02 | |||||
| Missing |
1893 |
9.0 |
|
|
|
|
0.11 |
0.09 |
0.14 |
|
| Performance status |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| 0 | 583 | 31.7 | 1.00 | |||||||
| 1–2 | 480 | 9.9 | 0.33 | 0.27 | 0.40 | |||||
| 3–4 | 15 | 0.7 | 0.05 | 0.03 | 0.09 | |||||
| Missing |
1816 |
9.2 |
|
|
|
|
0.41 |
0.34 |
0.50 |
|
| Histological subtype |
2894 |
10.1 |
|
|
|
|
|
|
|
<0.001 |
| Adenocarcinoma | 998 | 22.4 | 1.00 | |||||||
| Squamous cell | 1011 | 19.3 | 0.86 | 0.77 | 0.97 | |||||
| Large cell | 124 | 16.2 | 0.64 | 0.51 | 0.80 | |||||
| Non-small cell | 215 | 4.6 | 0.19 | 0.16 | 0.22 | |||||
| Other (specified) | 470 | 40.7 | 2.40 | 2.06 | 2.80 | |||||
| Small cell | 54 | 1.6 | 0.06 | 0.04 | 0.07 | |||||
| Unspecified carcinoma | 14 | 2.7 | 0.14 | 0.08 | 0.25 | |||||
| Neoplasm | 8 | 0.1 | 0.01 | 0.00 | 0.01 | |||||
Abbreviations: CCI score=Charlson comorbidity score; CI=confidence interval; IMD=Index of Multiple Deprivation; NSCLC=non-small cell lung cancer; OR=odds ratio; PS=performance status; SCLC=small cell lung cancer; SEP=socioeconomic position.