Table 1. Distribution of clinicopathological features by HIF-1α expression.
| Variable | HIF-1α<19 | HIF-1α⩾19 | P |
|---|---|---|---|
|
Gender | |||
| Male | 54 (47) | 60 (53) | 0.18 |
| Female |
15 (65) |
8 (35) |
|
|
Age (years) | |||
| <75 | 38 (58) | 27 (42) | 0.1 |
| ⩾75 |
31 (43) |
41 (57) |
|
|
Stage | |||
| 1 | 2 (40) | 3 (60) | 0.91 |
| 2 | 51 (50) | 50 (50) | |
| 3 | 14 (54) | 12 (46) | |
| 4a |
2 (40) |
3 (60) |
|
|
TURBT | |||
| Complete | 24 (46) | 28 (54) | 0.31 |
| Partial | 22 (47) | 25 (53) | |
| Biopsy |
21 (62) |
13 (38) |
|
|
Necrosis | |||
| Absent | 38 (59) | 26 (41) | 0.07 |
| Present |
31 (42) |
42 (58) |
|
|
Growth pattern | |||
| Papillary | 7 (50) | 7 (50) | 0.4 |
| Solid | 37 (56) | 29 (44) | |
| Both |
25 (44) |
32 (56) |
|
|
CIS | |||
| Absent | 45 (46) | 52 (54) | 0.21 |
| Present |
24 (60) |
16 (40) |
|
|
Hb (g dl−1) | |||
| <14 | 43 (57) | 33 (63) | 0.15 |
| ⩾14 |
26 (43) |
35 (57) |
|
|
CAIX | |||
| 0 | 34 (65) | 18 (35) | 0.004 |
| >0 |
30 (38) |
49 (62) |
|
|
GLUT1 | |||
| <100 | 36 (60) | 24 (40) | 0.006 |
| ⩾100 | 22 (34) | 43 (66) | |
Abbreviations: CAIX=carbonic anhydrase IX; CIS=carcinoma in situ; Hb=haemoglobin; HIF-1α=hypoxia-inducible factor-1α; TURBT=transurethral resection of bladder tumour.