Appendix Figure 1.

Tumour immune subtypes: showing a schematic overview of different stages of immune surveillance and tumour immune escape classified into seven immune subtypes, graded from 1 to 7 in ascending order from highly immunogenic and therefore high immune susceptibility (green) to high immune escape and low immune susceptibility (red), concerning combinations of CTL infiltration, NK-cell infiltration, Treg infiltration, classical HLA class I tumour expression, and HLA-EG tumour expression (de Kruijf et al, 2013).