Table 1. Univariate analysis showing the relationship between stage at diagnosis and various factors for patients with CRC.
| Factor | Overall (n=868) | Stage A or B (n=443) | Stage C or D (n=425) | OR (99% CI) |
|---|---|---|---|---|
| Provider delay median (IQR) weeks |
17 (8, 39) |
17 (9, 39) |
17 (8, 39) |
0.99 (0.99, 1.00) |
| Age median (IQR) years |
71 (64, 78) |
73 (66, 79) |
70 (62, 76) |
0.98 (0.96, 0.99) |
|
Gender | ||||
| Male | 491 (56.6) | 235 (53.1) | 256 (60.2) | 1.34 (0.94, 1.91) |
| Female |
377 (43.4) |
208 (47.0) |
169 (39.8) |
1.00 |
|
Smoking status | ||||
| Non-smoker | 326 (37.6) | 177 (40.0) | 149 (35.1) | 1.00 |
| Current smoker | 137 (15.8) | 65 (14.7) | 72 (16.9) | 1.32 (0.78, 2.23) |
| Ex-smoker | 191 (22.0) | 99 (22.4) | 92 (21.7) | 1.10 (0.69, 1.77) |
| Not known |
214 (24.7) |
102 (23.0) |
112 (26.4) |
1.30 (0.83, 2.05) |
|
Carstairs quintile | ||||
| 1 (least deprived) | 207 (24.3) | 98 (22.6) | 109 (26.0) | 1.00 |
| 2 | 230 (27.0) | 133 (30.7) | 97 (23.1) | 0.66 (0.40, 1.08) |
| 3 | 206 (24.2) | 100 (23.0) | 106 (25.3) | 0.95 (0.57, 1.58) |
| 4 | 149 (17.5) | 69 (15.9) | 80 (19.1) | 1.04 (0.60, 1.82) |
| 5 (most deprived) |
61 (7.2) |
34 (7.8) |
27 (6.4) |
0.71 (0.34, 1.52) |
| Charlson index (median (IQR) |
1 (0, 2) |
1 (0, 2) |
1 (0, 2) |
1.14 (1.05, 1.24) |
|
Place of presentation | ||||
| GP surgery | 676 (77.9) | 350 (79.0) | 326 (76.7) | 1.00 |
| GP home visit | 111 (12.8) | 59 (13.3) | 52 (12.2) | 0.95 (0.56, 1.61) |
| GP out of hours visit | 33 (3.8) | 12 (2.7) | 21 (4.9) | 1.88 (0.72, 4.87) |
| Other | 22 (2.5) | 10 (2.3) | 12 (2.8) | 1.29 (0.42, 3.95) |
| Not known |
26 (3.0) |
12 (2.7) |
14(3.3) |
1.25 (0.45, 3.52) |
|
Tumour grade | ||||
| I | 42 (4.9) | 36 (8.2) | 6 (1.44) | 1.00 |
| II | 550 (64.2) | 293 (66.7) | 257 (61.5) | 5.26 (1.65, 16.74) |
| III/IV | 147 (17.2) | 53 (12.1) | 94 (22.5) | 10.6 (3.14, 36.01) |
| Ungradeable |
118 (13.8) |
57 (13.0) |
61 (14.6) |
6.42 (1.88, 21.99) |
|
Type of hospital admission | ||||
| Elective admission | 631 (72.7) | 328 (74.0) | 303 (71.3) | 1.00 |
| Emergency admission |
237 (27.3) |
115 (26.0) |
122 (28.7) |
1.15 (0.78, 1.70) |
|
Symptom | ||||
| Constipation | 118 (13.6) | 49 (11.1) | 69 (16.2) | 1.56 (0.93, 2.61) |
| Rectal bleeding | 252 (29.0) | 140 (31.6) | 112 (26.4) | 0.77 (0.53, 1.14) |
| Abdominal pain | 251 (28.9) | 118 (26.6) | 133 (31.3) | 1.25 (0.85, 1.85) |
| Anorexia | 34 (3.9) | 12 (2.7) | 22 (5.2) | 1.96 (0.76, 5.03) |
| Weight loss | 79 (9.1) | 37 (8.4) | 42 (9.9) | 1.20 (0.65, 2.21) |
| Abdominal mass | 49 (5.7) | 29 (6.6) | 20 (4.7) | 0.71 (0.32, 1.52) |
Abbreviations: CI=confidence interval; GP=general practitioner; IQR=inter-quartile range; OR=odds ratio.
Values are n (%) unless otherwise stated.