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. 2014 Jul 3;111(3):461–469. doi: 10.1038/bjc.2014.352

Table 3. Relationship between patient and tumour factors and symptoms and signs with survival among CRC patients.

Factor Total (n=958) Deaths (n=762) HR 99% CI
Provider delay median (IQR) weeks
17 (8,39)
17 (8, 39)
0.99
0.992, 0.999
Age median (IQR) years
71 (64, 78)
74 (67, 79)
1.04
1.03, 1.05
Gender
Male 540 (56.4) 439 (81.3) 1.18 0.98, 1.42
Female
418 (43.6)
323 (77.3)
1.00
 
Smoking status
Never smoked 358 (37.4) 270 (75.4) 1.00  
Current smoker 149 (15.6) 117 (78.5) 1.14 0.86, 1.51
Ex-smoker 209 (21.8) 175 (83.7) 1.24 0.96, 1.59
Not known
242 (25.3)
200 (82.6)
1.33
1.04, 1.69
Carstairs deprivation quintile
1 (least deprived) 227 (24.1) 167 (73.6) 1.00  
2 255 (27.0) 195 (76.5) 1.05 0.80, 1.37
3 231 (24.5) 204 (88.3) 1.43 1.09, 1.87
4 165 (17.5) 133 (80.6) 1.32 0.97, 1.77
5 (most deprived)
65 (6.9)
51 (78.5)
1.17
0.77, 1.76
Charlson index median (IQR)
1 (0,2)
2 (0,2)
1.16
1.12, 1.20
Tumour grade
Grade I 46 (4.9) 35 (76.1) 1.00  
Grade II 571 (60.5) 434 (76.0) 1.09 0.69, 1.71
Grade III/IV 158 (16.7) 136 (86.1) 1.72 1.05, 2.80
Ungraded
169 (17.9)
145 (85.8)
1.75
1.08, 2.85
Place of original presentation
GP surgery 737 (76.9) 565 (76.7) 1.00  
GP home visit 128 (13.4) 121 (94.5) 1.86 1.43, 2.41
GP out of hours visit 37 (3.9) 30 (81.1) 1.12 0.69, 1.83
Others 25 (2.6) 21 (84.0) 1.39 0.78, 2.46
Missing
31 (3.2)
25 (90.7)
1.29
0.76, 2.18
Type of admission
No emergency admission 699 (73.0) 539 (77.1) 1.00  
Emergency admission
259 (27.0)
223 (86.1)
1.47
1.19, 1.80
Constipation
Yes 133 (13.9) 112 (84.2) 1.19 0.91, 1.55
No
825 (86.1)
650 (78.8)
1.00
 
Rectal bleeding
Yes 273 (28.5) 192 (70.3) 0.70 0.56, 0.87
No
685 (71.5)
570 (83.2)
1.00
 
Abdominal pain
Yes 273 (28.5) 224 (82.1) 1.14 0.93, 1.40
No
685 (71.5)
538 (78.5)
1.00
 
Anorexia
Yes 45 (4.7) 42 (93.3) 1.88 1.25, 2.83
No
913 (95.3)
720 (78.9)
1.00
 
Weight loss
Yes 94 (9.8) 82 (87.2) 1.33 0.98, 1.79
No
864 (90.2)
680 (78.7)
1.00
 
Abdominal mass
Yes 57 (6.0) 48 (84.21) 1.43 0.98, 2.11
No 901 (94.0) 714 (79.3) 1.00  

Abbreviations: CI=confidence interval; CRC=colorectal cancer; GP=general practitioner; HR=hazard ratio; IQR=inter-quartile range.

Values are n (%) unless otherwise stated.