Table 3. Relationship between patient and tumour factors and symptoms and signs with survival among CRC patients.
| Factor | Total (n=958) | Deaths (n=762) | HR | 99% CI |
|---|---|---|---|---|
| Provider delay median (IQR) weeks |
17 (8,39) |
17 (8, 39) |
0.99 |
0.992, 0.999 |
| Age median (IQR) years |
71 (64, 78) |
74 (67, 79) |
1.04 |
1.03, 1.05 |
|
Gender | ||||
| Male | 540 (56.4) | 439 (81.3) | 1.18 | 0.98, 1.42 |
| Female |
418 (43.6) |
323 (77.3) |
1.00 |
|
|
Smoking status | ||||
| Never smoked | 358 (37.4) | 270 (75.4) | 1.00 | |
| Current smoker | 149 (15.6) | 117 (78.5) | 1.14 | 0.86, 1.51 |
| Ex-smoker | 209 (21.8) | 175 (83.7) | 1.24 | 0.96, 1.59 |
| Not known |
242 (25.3) |
200 (82.6) |
1.33 |
1.04, 1.69 |
|
Carstairs deprivation quintile | ||||
| 1 (least deprived) | 227 (24.1) | 167 (73.6) | 1.00 | |
| 2 | 255 (27.0) | 195 (76.5) | 1.05 | 0.80, 1.37 |
| 3 | 231 (24.5) | 204 (88.3) | 1.43 | 1.09, 1.87 |
| 4 | 165 (17.5) | 133 (80.6) | 1.32 | 0.97, 1.77 |
| 5 (most deprived) |
65 (6.9) |
51 (78.5) |
1.17 |
0.77, 1.76 |
| Charlson index median (IQR) |
1 (0,2) |
2 (0,2) |
1.16 |
1.12, 1.20 |
|
Tumour grade | ||||
| Grade I | 46 (4.9) | 35 (76.1) | 1.00 | |
| Grade II | 571 (60.5) | 434 (76.0) | 1.09 | 0.69, 1.71 |
| Grade III/IV | 158 (16.7) | 136 (86.1) | 1.72 | 1.05, 2.80 |
| Ungraded |
169 (17.9) |
145 (85.8) |
1.75 |
1.08, 2.85 |
|
Place of original presentation | ||||
| GP surgery | 737 (76.9) | 565 (76.7) | 1.00 | |
| GP home visit | 128 (13.4) | 121 (94.5) | 1.86 | 1.43, 2.41 |
| GP out of hours visit | 37 (3.9) | 30 (81.1) | 1.12 | 0.69, 1.83 |
| Others | 25 (2.6) | 21 (84.0) | 1.39 | 0.78, 2.46 |
| Missing |
31 (3.2) |
25 (90.7) |
1.29 |
0.76, 2.18 |
|
Type of admission | ||||
| No emergency admission | 699 (73.0) | 539 (77.1) | 1.00 | |
| Emergency admission |
259 (27.0) |
223 (86.1) |
1.47 |
1.19, 1.80 |
|
Constipation | ||||
| Yes | 133 (13.9) | 112 (84.2) | 1.19 | 0.91, 1.55 |
| No |
825 (86.1) |
650 (78.8) |
1.00 |
|
|
Rectal bleeding | ||||
| Yes | 273 (28.5) | 192 (70.3) | 0.70 | 0.56, 0.87 |
| No |
685 (71.5) |
570 (83.2) |
1.00 |
|
|
Abdominal pain | ||||
| Yes | 273 (28.5) | 224 (82.1) | 1.14 | 0.93, 1.40 |
| No |
685 (71.5) |
538 (78.5) |
1.00 |
|
|
Anorexia | ||||
| Yes | 45 (4.7) | 42 (93.3) | 1.88 | 1.25, 2.83 |
| No |
913 (95.3) |
720 (78.9) |
1.00 |
|
|
Weight loss | ||||
| Yes | 94 (9.8) | 82 (87.2) | 1.33 | 0.98, 1.79 |
| No |
864 (90.2) |
680 (78.7) |
1.00 |
|
|
Abdominal mass | ||||
| Yes | 57 (6.0) | 48 (84.21) | 1.43 | 0.98, 2.11 |
| No | 901 (94.0) | 714 (79.3) | 1.00 | |
Abbreviations: CI=confidence interval; CRC=colorectal cancer; GP=general practitioner; HR=hazard ratio; IQR=inter-quartile range.
Values are n (%) unless otherwise stated.