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. 2014 Jul 23;15:84. doi: 10.1186/1471-2350-15-84

Table 2.

mtDNA variants in 1 Han Chinese subject (II-2) with hypertension and 1 Han Chinese control subject

Gene Position Replacement Conservation (H/M/B/X)* rCRS† II-2 Control Previously reported‡ Amino acid change
D-loop
 73
 A to G
  
 A
 G
 G
 Y
  
 
 152
 T to C
  
 T
 C
 C
 Y
  
 
 263
 A to G
  
 A
 G
 G
 Y
  
 
 310
 T to C
  
 T
 C
 C
 Y
  
 
 489
 T to C
  
 T
 C
 C
 Y
  
12SrRNA
 1382
 A to C
 A/G/G/C
 A
 C
 C
 Y
 rRNA
 
 1438
 A to G
 A/A/C/A
 A
 G
 G
 Y
 rRNA
16SrRNA
 2706
 A to G
 A/G/G/A
 A
 G
 G
 Y
 rRNA
 
 3010
 G to A
 G/T/G/A
 G
 A
 A
 Y
 rRNA
ND1
 3975
 C to T
 C/C/A/C
 C
 T
 C
 Y
 syn
 
 4260
 C to T
 C/M/C/T
 C
 T
 T
 Y
 syn
tRNA Ile
 4329
 C to G
 C/C/C/C
 C
 G
 C
 N
  
tRNA Met
 4467
 C to A
 C/C/C/C
 C
 A
 C
 N
  
COII
 8020
 G to A
 G/P/C/A
 G
 A
 A
 Y
 syn
ATPase8
 8414
 C to T
 C/A/C/A
 C
 T
 T
 Y
 L-F
ATPase6
 8701
 A to G
 A/I/F/T
 A
 G
 G
 Y
 T-A
COIII
 9824
 T to A
 T/F/L/C
 T
 A
 A
 Y
 syn
ND3
 10398
 A to G
 A/E/E/A
 A
 G
 G
 Y
 T-A
 
 10400
 C to T
 C/I/T/E
 C
 T
 T
 Y
 syn
ND4
 10873
 T to C
 T/T/T/C
 T
 C
 C
 Y
 syn
 
 11984
 T to A
 T/A/S/T
 T
 A
 T
 Y
 Y-H
ND6
 14580
 A to T
  
 A
 T
 T
 Y
 syn
 
 14587
 A to C
  
 A
 C
 C
 Y
 syn
 
 14605
 A to G
  
 A
 G
 G
 Y
 syn
 
 14668
 C to T
  
 C
 T
 T
 Y
 syn
Cytb
 14783
 T to C
 T/F/K/A
 T
 C
 C
 Y
 syn
 
 15043
 G to A
  
 G
 A
 A
 Y
 syn
 
 15301
 G to A
  
 G
 A
 A
 Y
 syn
 
 15326
 A to G
 A/L/S/A
 A
 G
 G
 Y
 T-A
D-loop
 16223
 C to T
  
 C
 T
 T
 Y
  
 
 16311
 T to C
  
 T
 C
 C
 Y
  
  16362 T to C   T C C Y  

*Data show the conservation of amino acid for polypeptides or nucleotide for rRNAs, in human (H), mouse (M), bovine (B), and Xenopus laevis (X).

†Cambridge sequence.

‡See http://www.mitomap.org.