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Heart weight to body weight ratio of mice. A, Body weights (BW) of the AE3 null (ae3-/-, black bar), heterozygous (ae3+/-, red bar) and the WT (ae3+/+, open bar) littermates were measured. B, Hearts, surgically removed from anaesthetized mice and trimmed of extra-cardiac and atrial tissue, were measured to obtain the ventricular weight (heart weight, HW). C, HW/BW, an index of hypertrophy, was calculated. *P<0.05 (n=8 mice/ group).
