Table 5. Effect of SA vs. Non-SA from Logistic Regression Models with Significant Interaction Terms of SA Diagnosis vs. Non-SA diagnosis.
Multivariable regression for outcomes with significant interactions. Present diagnosis of sleep apnea is the effect variable.
| Interaction Terms c | Adjusted OR (95% CI) a | Adjusted p-value a | c-statistic | ||
|---|---|---|---|---|---|
| Mechanical Ventilation | |||||
| Complicated Hypertension = No | COPD = No | 13.80 (11.53, 16.52) | <0.0001 | 0.83 | |
| COPD = Yes | 8.01 (6.19, 10.36) | <0.0001 | |||
| Complicated Hypertension = Yes | COPD = No | 5.30 (3.62, 7.74) | <0.0001 | ||
| COPD = Yes | 3.07 (2.04, 4.64) | <0.0001 | |||
| Non-Invasive Ventilation | |||||
| Complicated Hypertension = No | COPD = No | 46.12 (33.88, 62.77) | <0.0001 | 0.88 | |
| COPD = Yes | 16.20 (10.95, 23.97) | <0.0001 | |||
| Complicated Hypertension = Yes | COPD = No | 15.62 (8.53, 28.60) | <0.0001 | ||
| COPD = Yes | 5.49 (2.92, 10.30) | <0.0001 | |||
| ICU Utilization | |||||
| Male | 2006 | 1.86 (1.49, 2.30) | <0.0001 | 0.73 | |
| 2007 | 1.82 (1.49, 2.23) | <0.0001 | |||
| 2008 | 2.05 (1.70, 2.48) | <0.0001 | |||
| 2009 | 1.37 (1.13, 1.67) | <0.0001 | |||
| 2010 | 1.37 (1.09, 1.72) | 0.0005 | |||
| Female | 2006 | 2.28 (1.82, 2.84) | <0.0001 | ||
| 2007 | 2.23 (1.82, 2.73) | <0.0001 | |||
| 2008 | 2.52(2.09, 3.04) | <0.0001 | |||
| 2009 | 1.69 (1.38, 2.05) | <0.0001 | |||
| 2010 | 1.68 (1.34, 2.11) | <0.0001 | |||
| Telemetry/Stepdown Unit Utilization | |||||
| Complicated Hypertension = No | Obesity = No | 2006 | 1.81 (1.47, 2.23) | <0.0001 | 0.68 |
| 2007 | 1.49 (1.24, 1.78) | <0.0001 | |||
| 2008 | 1.40 (1.19, 1.65) | 0.0584 | |||
| 2009 | 1.73 (1.52, 1.96) | 0.0213 | |||
| 2010 | 1.54 (1.33, 1.78) | 0.0268 | |||
| Obesity = Yes | 2006 | 2.17 (1.73, 2.72) | <0.0001 | ||
| 2007 | 1.78 (1.47, 2.17) | <0.0001 | |||
| 2008 | 1.68 (1.41, 2.00) | 0.0689 | |||
| 2009 | 2.07 (1.79, 2.39) | 0.0262 | |||
| 2010 | 1.85 (1.58, 2.16) | 0.0309 | |||
| Complicated Hypertension = Yes | Obesity = No | 2006 | 1.25 (0.91, 1.73) | >0.99 | |
| 2007 | 1.03 (0.76, 1.39) | >0.99 | |||
| 2008 | 0.97 (0.73, 1.29) | 0.1853 | |||
| 2009 | 1.19 (0.91, 1.57) | 0.17 | |||
| 2010 | 1.07 (0.80, 1.41) | 0.1773 | |||
| Obesity = Yes | 2006 | 1.50 (1.08, 2.08) | 0.0047 | ||
| 2007 | 1.23 (0.91, 1.67) | 0.2089 | |||
| 2008 | 1.16 (0.87, 1.55) | 0.1901 | |||
| 2009 | 1.43 (1.08, 1.89) | 0.1731 | |||
| 2010 | 1.28 (0.96, 1.69) | 0.1801 | |||
| Increased Length of Hospitalization | |||||
| Obesity = No | 1.12 (1.06, 1.18) | <0.0001 | 0.65 | ||
| Obesity = Yes | 1.23 (1.15, 1.31) | <0.0001 | |||
(Reference = no sleep apnea diagnosis).
a
All 95% CIs and the associated p-values were both Bonferroni corrected for multiple comparisons
b
All unadjusted models had p-values < 0.001
c
All interaction terms had p-values < 0.001