Table 2.
Risk of pancreatic cancer associated with measures of IgE
| Cases (N=283) N (%) | Controls (N=544) N (%) | Odds Ratio (95% CI) | |
|---|---|---|---|
| Total IgE | |||
| Normal (<25 kU/L) | 113 (40) | 224 (41) | 1 |
| Borderline (25-100 kU/L) | 87 (31) | 192 (35) | 0.84 (0.59-1.20) |
| Elevated (>100 kU/L) | 81 (29) | 126 (23) | 1.22 (0.84-1.78) |
| >100-310 kU/L | 45 (16) | 79 (15) | 1.09 (0.68-1.73) |
| >310 kU/L | 36 (13) | 47 (9) | 1.42 (0.85-2.37) |
| Median (Range) | 32.7 (1 - 12662) | 31.9 (1 - 4099) | |
| Geometric Mean (SD) | 41.3 (5.26) | 35.5 (4.66) | |
| IgE to respiratory allergens | |||
| Negative (<35 kU/L) | 198 (70) | 392 (72) | 1 |
| Positive (≥35 kU/L) | 85 (30) | 150 (28) | 1.16 (0.84-1.61) |
| IgE to food allergens | |||
| Negative (<35 kU/L) | 257 (91) | 506 (93) | 1 |
| Positive (≥35 kU/L) | 26 (9) | 35 (6) | 1.57 (0.90-2.74) |
Odds ratios estimated using conditional logistic regression adjusting for smoking (for total IgE and IgE to respiratory allergens; never, former quit >15 years ago, former quit <15 years ago, current) or study center (for IgE to food allergens)