Table 10.
Medications with Health Canada–approved indications for anxiety and related disorders
| Anxiety disorders | Panic disorder | Social anxiety disorder | Obsessive–compulsive disorder | Generalized anxiety disorder | Posttraumatic stress disorder | |
|---|---|---|---|---|---|---|
| ANTIDEPRESSANTS | ||||||
| SSRIs | ||||||
| Escitalopram (Cipralex®) | X | X | ||||
| Fluoxetine (Prozac®) | X | |||||
| Fluvoxamine (Luvox®) | X | |||||
| Paroxetine (Paxil®) | X | X | X | X | X | |
| Paroxetine CR (Paxil® CR) | X | X | ||||
| Sertraline (Zoloft®) | X | X | ||||
| TCAs | ||||||
| Clomipramine | X | |||||
| Other antidepressants | ||||||
| Venlafaxine XR (Effexor® XR) | X | X | X | |||
| Duloxetine (Cymbalta®) | X | |||||
| AZAPIRONES | ||||||
| Buspirone (BuSpar®, Buspirex®) | X | |||||
| BENZODIAZEPINES* | X | |||||
Data from respective Canadian product monographs [84].
*Multiple generic and brand name products, consult product monographs: alprazolam, bromazepam, chlordiazepoxide, clorazepate, diazepam, lorazepam, and oxazepam are indicated for anxiety disorders; alprazolam is also indicated for panic disorder.
CR = controlled release; SSRI = selective serotonin reuptake inhibitor; TCA = tricyclic antidepressant; XR = extended release.