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. Author manuscript; available in PMC: 2015 Aug 15.
Published in final edited form as: J Immunol. 2014 Jul 14;193(4):1701–1708. doi: 10.4049/jimmunol.1400281

Figure 2. Some SAP variants have an altered effect on human fibrocyte differentiation.

Figure 2

PBMCs were incubated for 5 days in the presence of WT SAP or SAP variants. Compared to WT SAP, the SAP variants K130V and Q55A were more effective inhibitors of fibrocyte differentiation, whereas E126A and E153A had reduced activity. Values are fibrocyte count normalized to the no-SAP control ± SEM, n=3–5. The data were fit to sigmoidal dose response curves with variable Hill coefficients. The absence of error bars indicates that the error was smaller than the plot symbol.