Figure 1.

Expression of Meig1 mRNA and protein is underdetectable in the testis of the Hsp2-Cre; Meig1flox/flox mice. Total testicular RNA and protein were extracted from adult Meig1flox/flox and Hsp2a-Cre; Meig1flox/flox mice. Northern blot (A) was conducted using a full-length Meig1 cDNA as the probe; Western blot (B) was performed using an anti-MEIG1 antibody. Notice that there were no detectable Meig1 mRNA and protein in the testis of Hsp2a-Cre; Meig1flox/flox mice.