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. 2014 Jul 29;4(7):e005094. doi: 10.1136/bmjopen-2014-005094

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

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Schematic illustrating the assumptions made about the frequency of injection and monitoring consultations within the costing analysis. The consultations required by patients on discontinuous treatment will depend on when they met treatment failure criteria; patient 2 met the retreatment criteria at visits 0, 7 and 11. ✓ Relevant consultation cost was applied. ? The cost of fundus fluorescein angiography (FFA) was applied if clinically indicated: for discontinuous patients, this was applied whenever the patient had FFA in the trial; for continuous patients, the proportion of patients having FFA was based on estimated use in routine clinical practice. X No consultation cost was applied as the participant missed the visit.