. 2014 Jul 30;4(7):e005090. doi: 10.1136/bmjopen-2014-005090

Table 2.

Meta-analysis of withdrawal rate across included studies

Outcome	Intervention	Comparator	Studies	N	Fixed effects
Outcome	Intervention	Comparator	Studies	N	RR (95% CI)	p Value	I² (%)
Total withdrawals	Nicergoline	Placebo	8	1234	0.92 (0.70 to 1.21)	0.57	0
Total withdrawals	Nicergoline	Active agents	3	201	0.45 (0.10 to 1.95)	0.28	18
Withdrawals due to AE	Nicergoline	Placebo	3	565	1.13 (0.61 to 2.09)*	0.7	0

*RR value greater than 1 denotes higher rate of AEs with nicergoline compared with the comparator drug and a value less than 1 denotes vice versa.

AE, adverse event.