Table 4.
Sensitivity analysis on the risk factors for failure in enhanced recovery protocol after major hepatobiliary and pancreatic surgery
| Common-effect RR (95% CI) | p Value | |
|---|---|---|
| ICU admission | ||
| None | 1.000 | 0.202 |
| Elective | 0.505 (0.176 to 1.444) | |
| Adjusted cotinine concentration (ng/mL)* | 1.001 (1.000 to 1.001) | <0.001 |
| ALT/GPT (IU/L)† | ||
| Normal | 1.000 | <0.001 |
| High | 4.626 (2.097 to 10.207) | |
| Any postoperative morbidity | ||
| None | 1.000 | 0.007 |
| Present on day 3 | 2.657 (1.312 to 5.379) | |
*Active smokers commonly defined as urinary cotinine concentration >50 ng/mL.21
†High ALT/GPT defined as more than 67 IU/L in men and more than 55 IU/L in women.
ALT/GPT, alanine transaminase/glutamic-pyruvic transaminase; ICU, intensive care unit; RR, relative risk.