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. Author manuscript; available in PMC: 2014 Aug 15.

Published in final edited form as: Cancer. 2013 Jun 12;119(16):3027–3033. doi: 10.1002/cncr.28152

Table 4.

Mutational Analysis

	Lynch Syndrome			Sporadic

	EC	Hyperplasia	Benign	EC	CAH	Benign

	(n=29)	(n=8)	(n=30)	(n=58)	(n=16)	(n=10)
PIK3CA	4 (13.8%)	0	1 (3.3%)	23 (39.7%)^*	1 (6.3%)	0
KRAS	1 (3.4%)	0	0	5 (8.6%)	0	0
CTNNB1	2 (6.9%)	0	1 (3.3%)	18 (31.0%)^*	0	1 (10%)
LKB1	0	0	0	1 (1.7%)	0	0
AKT	0	0	0	1 (1.7%)	0	1 (10%)

^*

p<0.05 compared to Lynch Syndrome EC