Table 7.

Grade 3–4 NCI-CTCAE non-haematological toxicity in the HSCT arm of studies reporting aggregate case series data

Study	N events/ N evaluated patients	Specification
Aggregate comparative data
Bui-Nguyen et al21	11/38	Digestive (N=8); infection (N=2); pain (N=1)
Aggregate case series data
Bertuzzi et al22	NR	NA
Bisogno et al23	1/14	Mucositis grade 4
Blay et al24	16/24	Neurological grade 4 (N=1); lung grade 3/4 (N=2); renal grade 3/4 (N=5); nausea/vomiting grade 3/4 (N=8)
Bokemeyer et al25	8/16	No grade 4; neurological (N=1); renal (N=2); infection (N=1); mucositis (N=2); nausea/emesis (N=2)
Cook et al26	NR	NA
Philippe-Chomette et al27	NR	NA

HSCT, autologous haematopoietic stem cell transplantation following high-dose chemotherapy; N, number; NA, not applicable; NR, not reported; NCI-CTCAE, National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) grade III–IV.¹⁴