Table 2.
A Summary of Mesenchymal Stem Cell–Microbial Interaction Outcomes
| Outcome of MSC-microbe interaction | Pathogenic organism model (ST) | Probiotic organism model (LB) |
|---|---|---|
| Adherence vs. invasion | Invasion | Adherence |
| Viability | Did not induce cell death | Did not induce cell death |
| Proliferation rate | Not affected | Not affected |
| Migration | Inhibited | Not affected |
| CD54 expression | Increased | Not affected |
| APC phenotype shift | None | None |
| Immunomodulatory gene expression | ++++ | + |
| Immunomodulatory factor secretion | ++++ | + |
| Inhibition of T cell proliferation | Augmented | Not affected |
APC, antigen presenting cell; MSC, mesenchymal stem cell.