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Interstitial collagen III deposition with chronic dehydration. Wild-type mice with water provided only at night show increased interstitial fibrosis (b), compared with other groups. WT-WAT (a); WT-Control (c); KHK-KO, WAT (d); WAN (e); and Control (f). Scale bar=50 mm. KHK-KO, fructokinase knockout; WAN, water at night; WAT, water all time; WT, wild type.
