Skip to main content
. 2014 Aug 4;6:198. doi: 10.3389/fnagi.2014.00198

Figure 1.

Figure 1

mRNA expression analysis of glial activators and markers in sCJD is shown. RT-qPCR analysis of glial activators and markers in the frontal cortex and cerebellum of control and sCJD MM1 and VV2 subtypes: (A) LIF, (B) GFAP, (C) CD11b, (D) IBA1, (E) CD68, and (F) OLIG2. Values are normalized using GUS-b and GAPDH as internal controls. Frontal cortex: control (Con, n = 15), MM1 (n = 15), VV2 (n = 15); cerebellum: control (Con, n = 15), MM1 (n = 15), VV2 (n = 10). Data are represented as the mean SEM. *p < 0.05, **p < 0.01, ***p < 0.001 sCJD compared with control cases; #p < 0.05, ## p < 0.01 sCJD VV2compared with sCJD MM1 cases (Tukey’s post hoc test).