Table 1.
Analysis of LPS distribution in liver sections.
F4/80 | + | + | − | − | |
CD144 | + | − | + | − | |
1 hr | LPS | 83±9% | 0.4±0.5% | 13±9% | 4.0±4.7% |
LPS-HDL | 49±11%*** | 0.7±1.8% | 35±5%*** | 15.4±10.2%* | |
4 hrs | LPS | 94±4% | 0 ± 0% | 5.9±3.9% | 0.2±0.3% |
LPS-HDL | 72±14%* | 0.2±0.8% | 25±14% | 3.4±4.0% |
The percentage of the total FITC-LPS that overlapped or was adjacent to Kupffer cells (F4/80+) or sinusoidal endothelial cells (CD144+) was estimated as described in Methods and shown as mean ± SD (n=6 images) derived from 3 mice/group. Asterisks denote significant difference from the control (LPS) group
p<0.05,
p<0.01,
p<0.001.