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. 2014 Jul 22;15:86. doi: 10.1186/1471-2156-15-86

Table 2.

Significantly differentiated regions

Discovery mechanism Chr Start (Mb) End (Mb) FST (window size) XP-EHH (direction a ) iHS (INS) iHS (GIH) Genes
F ST
4
17.0
17.5
Top 0.1% (500 kb)
No evidence
No evidence
Top 1%
QDPR, FAM184B, CLRN2, DCAF16, LAP3, MED28
 
5
105.4
105.7
Top 0.1% (100 kb)
Top 0.5% (negative)
No evidence
No evidence
-
 
8
85.0
85.6
Top 0.1% (500 kb)
Top 0.5% (negative)
No evidence
No evidence
RALYL
 
15
45.7
46.2
Top 0.1% (500 kb)
Top 0.5% (negative)
No evidence
No evidence
SLC24A5, MYEF2, CTXN2, SLC12A1
 
17
41.3
41.5
Top 0.1% (100 kb)
Top 0.5% (positive)
No evidence
No evidence
MAPT, STH, KIAA1267
iHS
12
23.0
23.3
Top 1% (100 kb)
No evidence
No evidence
Top 0.1%
-
 
12
58.3
58.6
No evidence
Top 0.5% (negative)
No evidence
Top 0.1%
SLC16A7
  12 80.3 80.6 Top 1% (100 kb) No evidence Top 0.1% No evidence ACSS3, PPFIA2

Regions identified and validated across the genome by different discovery mechanisms using three population genetics metrics calculated from the data for GIH and INS.

aPositive direction indicates evidence of positive selection in INS while negative direction indicates evidence of positive selection in GIH.