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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Neurochem Int. 2014 Apr 18;72:14–21. doi: 10.1016/j.neuint.2014.04.006

Figure 3. BDNF Promotes the Formation of GABAAR-Gephyrin Associations.

Figure 3

Incubation with BDNF and/or TrkB-Fc was carried out for 2 days. Cell lysates were immunoprecipitated using 5 μg of an antibody directed against the α1 subunit of GABAAR or 5 μg of control IgG. (A) Gephyrin immunoreactivity associated to GABAAR was detected by western blot. (B) Quantitation of 6 independent experiments it is presented as the mean ± S.E.M. BDNF triggers a significant increase in the amount of gephyrin immunoreactivity associated with GABAAR and this effect appears to be dependent on the addition of exogenous BDNF (**p<0.01 compared to BDNF-treated cells by ANOVA).