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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Cell Calcium. 2014 Jun 6;56(2):96–107. doi: 10.1016/j.ceca.2014.05.004

Figure 8. Effects of potential RyR modulators on open probability.

Figure 8

Experiments were performed wit each compound listed in the presence of 1 μM Ca2+, and separately in the presence of 100 μM Ca2+ to demonstrate maximal achievable Po. Mean (± SE) open probabilities were calculated for each experiment. A bar chart was constructed for the grouped data (n ≥ 4 for each condition) and plotted for each condition. Only caffeine and 100 μM Ca2+ had a significant effect on channel open probability in the presence of 1 μM Ca2+.*p < 0.05.