Table 6. Growth at 18 to 22 months according to treatment assignment (adjusted analysis).
Variable | Dexamethasone n=76 | Placebo n=68 | RR (95% CI) | P-value |
---|---|---|---|---|
Male – no. (%) | 38(50) | 33(49) | 0.86 | |
Clinical steroid use – no. (%) | 28(37) | 39(57) | 0.01 | |
Growth parameters | Mean ± S.D | |||
Weight – kg. | 10.3±1.6 | 10.3±1.4 | 0.98 | |
Length – cm. | 80.3±4.9 | 80.0±4.2 | 0.60 | |
Head circumference - cm | 46.8±2.2 | 46.6±2.1** | 0.59 | |
Growth < 10th percentile | ||||
Weight – no. (%) | 38(50) | 27(40) | 1.16(0.81,1.66) | 0.42 |
Length - no. (%)* | 19(25) | 21(31) | 0.76(0.45,1.27) | 0.29 |
Head circumference – no. (%)* | 21(28) | 19(28)** | 0.96(0.57,1.63) | 0.88 |
RR is the relative risk of the outcome in the dexamethasone group as compared with the placebo group. CI denotes confidence interval.
Not adjusted for center because of convergence issues.
In the placebo group, n=67 for head circumference