Table 2.

Comparison of Tests To Screen for Prediabetes

Fasting plasma glucose	Hemoglobin A1c
• Higher sensitivity compared to A1c in adult populations (in adults up to one third more diagnosed)50 • Unaffected by conditions associated with high red blood cell turnover (e.g., anemia, blood transfusion, pregnancy) • Less expensive and more convenient compared to OGTT • Low reproducibility	• Fasting is not required. • Low intraindividual variability • Less day-to-day variability with illness or stress • Reflects glycemic levels for the past 3 months • Good predictor of diabetes-related complications in adults50

OGTT, oral glucose tolerance test; A1c, glycosylated hemoglobin.