Table 3.

Comparison of Prevalence of Comorbid Conditions Coded from Both Indices

	Condition	Chart-based ACE-27	Claims-based CCI	p Value*	Kappa†	Yule’s Y‡	95% CI for Yule’s Y
1	MI	317 (5%)	176 (3%)	<0.001	0.55	0.84	0.81–0.87
3	CHF	261 (4%)	219 (4%)	0.0033	0.56	0.80	0.77–0.83
6	Venous+PAD	270 (4%)	96 (2%)	<0.001	0.25	0.68	0.62–0.74
7	PAD	141 (2%)	96 (2%)	0.0002	0.37	0.76	0.71–0.81
8	Respiratory	834 (14%)	722 (12%)	<0.001	0.63	0.74	0.72–0.76
9	Hepatic	129 (2%)	65 (1%)	<0.001	0.44	0.84	0.80–0.88
10	Stomach	63 (1%)	39 (0.6%)	0.015	0.03	0.40	0.09–0.70
12	Renal	189 (3%)	17 (0.3%)	<0.001	0.10	0.77	0.67–0.87
13	Diabetes	1051 (17%)	884 (14%)	<0.001	0.73	0.81	0.79–0.83
14	Stroke	241 (4%)	63 (1%)	<0.001	0.12	0.56	0.46–0.65
15	Dementia	88 (1%)	2 (0.03%)	<0.001	0.02	0.79	0.52–1.00
16	Paralysis	150.2%)	18 (0.3%)	0.59	0.06	0.67	0.38–0.96
19	Rheumatologic	155 (3%)	60 (1%)	<0.001	0.316	0.79	0.73–0.84
20	AIDS	32 (0.5%)	18(0.3%)	0.016	0.32	0.87	0.81–0.93
22	Malignancy	1046 (17%)	16 (0.3%)	<0.001	0.002	0.12	−0.16–0.40

^*McNemar’s test p value.

^†Kappa statistic is a measure of agreement that ranges from an expected value of 0 in case of agreement no more than expected by chance to a value of 1 in case of perfect agreement.

^‡Yule’s Y is a measure of association independent of the prevalence that ranges from −1 to 1. Values of Yule’s Y close to 0 indicate poor agreement and values of Yule’s Y closer to 1 indicate strong agreement.

ACE-27, Adult Comorbidity Evaluation-27; CCI-Charlson Comorbidity Index; MI, myocardial infarction; CHF, congestive heart failure; PAD, peripheral arterial disease; AIDS, acquired immunodeficiency syndrome.