Table 2.
Descriptive and univariate analysis of clinical risk factors for delirium following HSCT (n=51).
| Laboratory and Vitals (ref range) | Mean (Range; SD) | Hazard Ratio (95% CI) |
P-value uncorrected |
P-value corrected |
|---|---|---|---|---|
| Electrolytes | ||||
| Sodium (135-145 mEQ/L) | 0.98 (0.87-1.12) | 0.80 | 0.89 | |
| Delirium (n =16) | 136 (126-141; 3.9) | |||
| No delirium (n=34) | 136 (125-142; 3.9) | |||
| Magnesium (1.5-2.9 mg/dL) | 2.57 (0.85-7.80) | 0.09 | 0.36 | |
| Delirium (n=16) | 2.1 (1.3-2.8; 0.3) | |||
| No delirium (n=33) | 1.9 (1.5-2.8; 0.3) | |||
| Glucose (65-99 mg/dL) | 1.00 (0.99-1.00) | 0.48 | 0.74 | |
| Delirium (n=13) | 151 (75-262; 52) | |||
| No delirium (n=28) | 209 (72-868; 166) | |||
| Metabolic | ||||
| Blood urea nitrogen (10-20 ml/dL) | 1.05 (1.01-1.09) | 0.005 | 0.05 | |
| Delirium (n=16) | 27 (8-73; 17) | |||
| No delirium (n=34) | 18 (7-61; 11) | |||
| Creatinine (0.7-1.4 mg/dL) | 31.8 (5.60-180.79) | <0.0001 | 0.007 | |
| Delirium (n=16) | 1.1 (0.6-1.7; 0.3) | |||
| No delirium (n=34) | 0.8 (0.5-1.9; 0.3) | |||
| Creatinine Clearance (80-120 mL-min) | 0.97 (0.95-0.99) | 0.0006 | 0.01 | |
| Delirium (n=16) | 96 (40-197; 38) | |||
| No delirium (n=34) | 142 (13-334; 57) | |||
| Alkaline Phosphatase (40-129 U/L) | 0.98 (0.96-1.01) | 0.27 | 0.54 | |
| Delirium (n=11) | 67 (44-125; 26) | |||
| No delirium (n=17) | 83 (47-146; 33) | |||
| Aspartate Aminotransferase (0-37 u/l) | 0.99 (0.96-1.02) | 0.60 | 0.80 | |
| Delirium (n=13) | 23 (8-62; 17) | |||
| No delirium (n=21) | 24 (8-110; 22) | |||
| Bilirubin, Total (0.2-1.0 mg/dL) | 0.97 (0.78-1.20) | 0.77 | 0.89 | |
| Delirium (n=15) | 1.4(0.3-9.6; 2.3) | |||
| No delirium (n=26) | 1.7 (0.2-21.1; 4.1) | |||
| Albumin (3.4-4.8 g/dL) | 0.43 (0.10-1.75) | 0.24 | 0.51 | |
| Delirium (n=6) | 3.0 (1.7-3.5; 0.6) | |||
| No delirium (n=18) | 3.2 (2.8-4.2; 0.3) | |||
| Hematologic | ||||
| White Blood Cells (3.7-10.5 k/mm3) | 0.69 (0.32-1.50) | 0.35 | 0.63 | |
| Delirium (n=16) | 0.4 (0.1-2.5; 0.6) | |||
| No delirium (n=34) | 1.4 (0.1-9.0; 2.1) | |||
| Platelets (150-400 K/mm3) | 0.96 (0.92-1.01) | 0.14 | 0.36 | |
| Delirium (n=16) | 14 (3-45; 12) | |||
| No delirium (n=34) | 22 (5-71; 16) | |||
| Hemoglobin (11.9-17.7 g/dL) | 0.61 (0.39-0.97) | 0.04 | 0.25 | |
| Delirium (n=16) | 8.4 (6.7-10.6; 1.0) | |||
| No delirium (n=34) | 9.2(7.0-11.6; 1.0) | |||
| Vital Signs | ||||
| Weight (kg) | 0.99 (0.96-1.01) | 0.28 | 0.54 | |
| Delirium (n=16) | 83 (57-125; 16) | |||
| No delirium (n=34) | 91 (61-143; 21) | |||
| Oximetry (0-100%) | 0.82 (0.72-0.92) | 0.001 | 0.02 | |
| Delirium (n=15) | 92 (79-97; 4.5) | |||
| No delirium (n=32) | 94 (89-98; 1.9) | |||
| Pain score (0-10) | 1.17 (0.95-1.45) | 0.14 | 0.36 | |
| Delirium (n=15) | 3.5 (0-8; 2.9) | |||
| No delirium (n=30) | 1.7 (0-7; 2.1) | |||
| Temperature (36.1-37.2 C) | 1.40 (0.91-2.17) | 0.13 | 0.36 | |
| Delirium (n=16) | 38.5 (37.6-39.8; 0.7) | |||
| No delirium (n=33) | 37.8 (36.5-40.3; 0.9) |