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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Psychoneuroendocrinology. 2014 Jan 22;42:98–105. doi: 10.1016/j.psyneuen.2014.01.010

Figure 5. The corticosterone response to acute restraint was blunted by Mc4r loss-of-function.

Figure 5

a) The corticosterone response was blunted in both HET and HOM rats, relative to WT littermates, at 60 minutes following the onset of acute restraint (RM ANOVA, p (genotype × time) < 0.01). b) There was a significant effect of genotype to reduce the integrated area under the CORT: time curve (Kruskal-Walis, p < 0.05), though none of the posthoc comparisons were significant. Data presented as mean ± S.E.M. * P < 0.05 compared to WT littermates. n = 15 per group.