Skip to main content
. Author manuscript; available in PMC: 2015 Mar 8.
Published in final edited form as: Lancet. 2013 Aug 28;383(9920):911–922. doi: 10.1016/S0140-6736(13)60688-1

Table 7.

Research and Public Health Priorities for Delirium

Area Research Priorities Public Health Priorities
Recognition
  • Improve measurement for delirium: diagnosis, phenomenology, severity, and subtypes

  • Develop cost-effective approach for delirium evaluation and work-up

  • Improve coding and reimbursement

  • Educate clinicians and public about the importance and recognition of delirium

Epidemiology
  • Long-term follow-up studies of delirium to determine outcomes

  • Patient experience: distress, post- traumatic stress disorder

  • Genetic determinants of delirium risk

  • Risk stratification to identify high risk

  • Assess the economic and societal costs of delirium

  • Policy incentives to improve delirium recognition and management

  • Address caregiver burden

Pathophysiology
  • Neuroimaging approaches

  • ‘Deliriomics’ to identify biomarkers

  • Animal models for delirium

  • Improve funding for delirium research overall

  • Encourage interdisciplinary scientists to address the topic

Prevention and Treatment
  • Evaluate long-term effects of non- pharmacologic prevention strategies

  • Trials of medication reduction: more prudent, individualized approaches to sedation, anesthesia, and analgesia

  • Combined approaches to management, such as music, massage, exercise, cognitive rehabilitation, and sleep enhancement

  • Incentives for system-wide process and quality improvements in delirium detection, prevention and treatment

  • Provider education: delirium prevention and management approaches

  • Public education: avoid psychoactive drugs (including over-the-counter), limit alcohol use, encourage exercise, and enhance cognitive reserve

Adapted with permission from: Inouye SK et al. JAMA 1996; 275:852-857 Copyright © 1996 American Medical Association. All Rights Reserved