Table 3.

Extracellular purine content at time zero (0) and 24 hours in 100 μM-inosine-treated enriched astroglial cultures.

Analites	Concentration (μM)
	0	24 hours
Adenosine	1.7 ± 0.1	1.6 ± 0.4
Inosine	105 ± 1	9.0 ± 0.1***
Hypoxanthine	22.6 ± 0.1	127 ± 21**
Xanthine	8.5 ± 0.1	13 ± 2
Urate	20.3 ± 0.1	24 ± 4

Purine content of astrocyte medium was measured by high-performance liquid chromatography. Data are expressed as μM. Significance was determined by Student’s t test:

^**P < 0.01 and

^***P < 0.001 vs 0 time point value. Data are presented as means ± SEM of four experiments.